MINFLUX microscope installed

The new MINFLUX super-resolution microscope has been installed!

MINFLUX microscope

The brand new Abberior Super-resolution microscope is now installed in the Department of Physiology, Uni Bern.

MINFLUX microscope install combo

Everything arrived in 3 massive crates and after a little bit of sweating we got the breadboard with all optics assembled already on it into the …

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MINFLUX microscope for Physiology and Uni Bern

A new MINFLUX super-resolution microscope is coming to Physiology Bern!

MINFLUX microscope

The top image shows the Abberior Super-resolution microscope that enables fluorescence imaging with truly molcular resolution. The panel below shows proteins that are part of the nuclear pore complex (NPC) and exhibits the very high 3D resolution of the MINFLUX …

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Extracting PSFs with PYME

PYME PSF viewer

A brief tutorial

PYME is a very powerful framework but for that very reason also can be complex to use. In addition, the documentation often does not keep pace with the introduction of exciting new features. In a loose sequence of blog entries we will illustrate a few specific tasks …

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Our Lab in Physiological News Spring Edition

Physiological News

Phd student Carl Harrison has written a very nice perspective for the spring edition of Physiology News.

Carl gives an overview of our work on super-resolution imaging of clusters of RyR2 and why physiologists, mathematical modelers, biologists at large and everybody else should care about it.

For info, the sleeping …

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RyR Cell Reports paper is out!

RyRs Cell Reports

We have just published our paper on fully quantitative imaging of ryanodine receptors in Cell Reports. A good start to 2018! Using DNA based labeling we were able to push the optical resolution to new limits.

Here are our highlights:

  • With enhanced resolution, individual RyRs were observed within dense clusters …
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